Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Glycine dehydrogenase (decarboxylating), mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring), GLDC, GCSP
For WB starting dilution is: 1:1000
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
- Chang, C.Y., et al. Acta Paediatr Taiwan 49(1):35-37(2008)
- Kanno, J., et al. J. Med. Genet. 44 (3), E69 (2007)
- Kure, S., et al. Hum. Mutat. 27(4):343-352(2006)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This GLDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC.
2731
Glycine dehydrogenase (decarboxylating), mitochondrial
GLDC
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
113 kDa
P23378
229462870
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
P23378
Optimal dilutions for each application to be determined by the researcher.