ProSci

COLQ Antibody

Product Code:
 
PSI-60-634
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse stomach tissue lysates (35ug/lane).
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Western blot analysis in mouse stomach tissue lysates (35ug/lane).

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PSI-60-634-400ul400ul£626.00
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Further Information

Additional Names:
Acetylcholinesterase collagenic tail peptide, AChE Q subunit, Acetylcholinesterase-associated collagen, COLQ
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Mihaylova, V., et al. Brain 131 (PT 3), 747-759 (2008) :
  • Schreiner, F., et al. Neuromuscul. Disord. 17(3):262-265(2007)
  • Ting, A.K., et al. Chem. Biol. Interact. 157-158, 63-70 (2005) :
  • Dvir, H., et al. EMBO J. 23(22):4394-4405(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
NCBI Gene ID #:
8292
NCBI Official Name:
Acetylcholinesterase collagenic tail peptide
NCBI Official Symbol:
COLQ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q9Y215
Protein GI Number:
116241309
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y215
User NOte:
Optimal dilutions for each application to be determined by the researcher.