ProSci

LHFPL5 Antibody

Product Code:
 
PSI-55-170
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).

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PSI-55-170-400ul400ul£626.00
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Further Information

Additional Names:
Tetraspan membrane protein of hair cell stereocilia, Lipoma HMGIC fusion partner-like 5 protein, LHFPL5, TMHS
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis.
Background References:
  • Cosetti, M., et al. Ann. Otol. Rhinol. Laryngol. 117(11):827-833(2008)
  • Shabbir, M.I., et al. J. Med. Genet. 43(8):634-640(2006)
  • Longo-Guess, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 102(22):7894-7899(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This LHFPL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the C-terminal region of human LHFPL5.
NCBI Gene ID #:
222662
NCBI Official Name:
Tetraspan membrane protein of hair cell stereocilia
NCBI Official Symbol:
LHFPL5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q8TAF8
Protein GI Number:
74751349
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TAF8
User NOte:
Optimal dilutions for each application to be determined by the researcher.