NSJ Bioreagents

MUC1 Antibody

Product Code:
 
NSJ-R31426
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the MUC1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of MUC1 antibody and Lane 1: COLO320; 2: SW620; 3: HEPG2; 4: MCF-7; 5: Jurkat lysate; This glycoprotein is commonly visualized between 120~500 kDa.
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Western blot testing of MUC1 antibody and Lane 1: COLO320; 2: SW620; 3: HEPG2; 4: MCF-7; 5: Jurkat lysate; This glycoprotein is commonly visualized between 120~500 kDa.

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CodeSizePrice
NSJ-R31426-100ug100 ug£535.00
Quantity:
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Mucin 1 protein is encoded by the MUC1 gene in humans. This gene encodes a membrane-bound protein that is a member of the mucin family. Family members are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. MUC1 is a transmembrane protein normally expressed on the apical borders of secretory epithelial cells. Overexpression is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. It stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells. This protein also can suppress pulmonary innate immunity, and its anti-inflammatory activity may play an important modulatory role during microbial infection.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 1067-1083 (QELQRDISEMFLQIYKQ-human) were used as the immunogen for this MUC1 antibody.
Limitation:
This MUC1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P15941