NSJ Bioreagents

PD-L1 Antibody

Product Code:
 
NSJ-R31573
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the PD-L1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of human JK cells with PD-L1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= PD-L1 antibody.~
2 / 2
Western blot testing of human 1) PC-3, 2) placenta, 3) HepG2, 4) ThP-1, 5) K
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Flow cytometry testing of human JK cells with PD-L1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= PD-L1 antibody.~
Western blot testing of human 1) PC-3, 2) placenta, 3) HepG2, 4) ThP-1, 5) K

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CodeSizePrice
NSJ-R31573-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells
Application Note:
The stated application concentrations are suggested starting points. Titration of the PD-L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Programmed death-ligand 1, also known as CD274 or B7-H1 is a protein that in humans is encoded by the CD274 gene. It is a 33-70kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Upregulation on tumor MDCs downregulates T-cell immunity and PD-L1 blockade may represent an approach for cancer immunotherapy. It can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. It has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
29126
Immunogen:
Human partial recombinant protein (AA 45-290) was used as the immunogen for this PD-L1 antibody.
Limitation:
This PD-L1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human