NSJ Bioreagents

PLD1 Antibody

Product Code:
 
NSJ-R32213
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the PLD1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of 1) mouse heart, 2) human 22RV1 and 3) human HeLa cell lysate with PLD1 antibody. Expected/observed molecular weight: ~124 kDa.
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Western blot testing of 1) mouse heart, 2) human 22RV1 and 3) human HeLa cell lysate with PLD1 antibody. Expected/observed molecular weight: ~124 kDa.

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CodeSizePrice
NSJ-R32213-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the PLD1 antibody should be determined by the researcher.
Description:
By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 1-330 of human PLD1 were used as the immunogen for the PLD1 antibody.
Limitation:
This PLD1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
Q13393