NSJ Bioreagents

SAP97 Antibody / DLG1

Product Code:
 
NSJ-R32206
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the SAP97 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 2
Western blot testing of 1) rat lung, 2) mouse lung, 3) HeLa, 4) MM231, 5) COLO320, 6) A549 and 7) mouse NIH3T3 lysate with SAP97 antibody. Predicted molecular weight: ~103 kDa, rountinely observed at ~140 kDa (Ref 1).~
2 / 2
IHC testing of FFPE human pr
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Western blot testing of 1) rat lung, 2) mouse lung, 3) HeLa, 4) MM231, 5) COLO320, 6) A549 and 7) mouse NIH3T3 lysate with SAP97 antibody. Predicted molecular weight: ~103 kDa, rountinely observed at ~140 kDa (Ref 1).~
IHC testing of FFPE human pr

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NSJ-R32206-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
Optimal dilution of the SAP97 antibody should be determined by the researcher.
Description:
Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody.
Limitation:
This SAP97 antibody is available for research use only.
Localization:
Cytoplasmic, membrane
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q12959